tRNA-binding centers of Escherichia coli ribosomes and their structural organization

Problems concerning the interaction of tRNA with Escherichia coli ribosomes in different functional states were studied. These problems deal first of all with the number of tRNA-binding sites on ribosome, the conservation of the codon-anticodon interaction at the P-site and with regions of tRNA interacting with ribosome. The problems concerning structural organization of tRNA-binding centers are discussed in more detail.