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Ureogenesis in elasmobranch fishes
Affiliation:1. Evolution and Ecology Centre, School of Biological, Earth, and Environmental Sciences, University of New South Wales, Sydney, New South Wales, Australia;2. Division of Ecology and Evolution, Research School of Biology, College of Science, The Australian National University, Canberra, Australian Capital Territory, Australia;3. School of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia;4. Hawkesbury Institute for the Environment, Western Sydney University, New South Wales, Australia;5. Theoretical Sciences Visiting Program, Okinawa Institute of Science and Technology Graduate University, Onna 904-0495, Japan;6. Institute of Environmental Sciences, Jagiellonian University, Krakow, Poland
Abstract:
  • 1.(1) The following reactions have been directly demonstrated in extracts from acetone powders prepared from the livers of several species of elasmobranch fishes:(i) carbamyl phosphate+ornithine → citrulline(ii) citrulline+aspartate → urea.
  • 2.(2) There is strong circumstantial evidence that reaction (ii) proceeds by way of argininosuccinate and arginine.
  • 3.(3) Attempts to demonstrate a synthesis of carbamyl phosphate were unsuccessful.
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