Adenosine infusion increases plasma levels of VEGF in humans |
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Authors: | Thomas?H?Adair mailto:tadair@physiology.umsmed.edu" title=" tadair@physiology.umsmed.edu" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,Reid?Cotten,Jian-Wei?Gu,Janelle?S?Pryor,Kenneth?R?Bennett,Michael?R?McMullan,Preston?McDonnell,Jean-Pierre?Montani |
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Affiliation: | (1) Angiogenesis Research LaboratoriesCenter for Excellence in Cardiovascular-Renal Research, USA;(2) Department of Physiology, Biophysics University of Mississippi Medical Center Jackson, MS 39216, USA;(3) Department of Medicine University of Mississippi Medical Center Jackson, MS 39216, USA;(4) Institute of Physiology, University of Fribourg, 1700 Fribourg, Switzerland |
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Abstract: | ![]()
Background Many in vitro studies have shown that adenosine (Ado) can induce vascular endothelial growth factor (VEGF) mRNA and protein expression and stimulate endothelial proliferation. In the present study, we seek to determine whether Ado can increase circulating levels of VEGF protein in the intact human. |
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