Flavonoids from the bark and stems of Cassia fistula and their anti-tobacco mosaic virus activities |
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| Authors: | Wei Zhao Xiaoying Zeng Tao Zhang Lan Wang Guangyu Yang Yong-Kuan Chen Qiufen Hu Mingming Miao |
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| Affiliation: | 1. Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, PR China;2. Technology Center of Hongyun and Honghe Tobacco (Group) Co., Ltd., Kunming 650202, PR China;3. Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, PR China |
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| Abstract: | ![]()
Two new flavonoids, fistulaflavonoids B and C (1–2), together with five known flavonoids (3–7) were isolated from the bark and stems of Cassia fistula. Their structures were determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidences. The anti-tobacco mosaic virus (anti-TMV) activity of the isolated flavonoids was also evaluated. The results showed that compounds 1 and 2 showed high anti-TMV activity with inhibition rate of 28.5% and 31.3%, which is higher than that of Ningnanmycin (24.7%). Compounds 4–7 showed modest anti-TMV activity with inhibition rate of 18.5%, 22.7%, 16.4%, and 15.3%, respectively. |
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