3-hydroxy fatty acids found in capsules of Cryptococcus neoformans |
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Authors: | Sebolai Olihile M Pohl Carolina H Botes Piet J Strauss Catharina J van Wyk Pieter W J Botha Alfred Kock Johan L F |
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Affiliation: | UNESCO MIRCEN: Industrial Biotechnology, Department of Microbial, Biochemical and Food Biotechnology, University of the Free State, P.O. Box 339, Bloemfontein, South Africa. |
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Abstract: | Using immunofluorescence confocal laser scanning microscopy, immunogold transmission electron microscopy and gas chromatography--mass spectrometry, we demonstrated the presence of 3-hydroxy fatty acids in Cryptococcus neoformans. Our results suggest that these oxylipins accumulate in capsules where they are released as hydrophobic droplets through tubular protuberances into the surrounding medium. |
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