Copper absorption in young men fed adequate and low zinc diets |
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Authors: | Judith R Turnlund Leslie Wada Janet C King William R Keyes Lorra L Acord |
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Institution: | (1) Western Human Nutrition Research Center, USDA, ARS, 800 Buchanan Street, 94710 Albany, CA;(2) University of California, 94720 Berkeley, CA |
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Abstract: | Copper absorption was measured at two levels of dietary zinc in six healthy young men who were confined to a metabolic unit
for a 75 d study of zinc utilization. A diet of conventional foods was fed, providing either 16.5 or 5.5 mg zinc and 1.3 mg
copper daily. Copper absorption was determined by feeding65Cu, a stable isotope of copper, once during the 16.5 mg Zn diet and near the beginning and end of the 5.5 mg Zn diet. Apparent
copper absorption averaged 48.1% when the 16.5 mg Zn diet was fed. This was significantly higher than the averages of 37.2
and 38.5% when the 5.5 mg Zn diet was fed. Absorption also differed significantly among subjects. Fecal copper did not differ
between diets or among subjects. All subjects were in positive copper balance at both levels of dietary zinc. These results
suggest that a dietary zinc intake slightly above the Recommended Dietary Allowance of 15 mg/d does not increase fecal copper
loss and does not interfere with copper absorption. |
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Keywords: | Copper zinc absorption stable isotopes nutrient interactions bioavailability |
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