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α—人心房钠尿因子对离体豚鼠心肌收缩力和动作电位...
引用本文:吴伟建,夏强.α—人心房钠尿因子对离体豚鼠心肌收缩力和动作电位...[J].生理学报,1991,43(2):195-198.
作者姓名:吴伟建  夏强
摘    要:

关 键 词:心房钠泵因子  心肌  动作电位时程

Effect of alpha-human atrial natriuretic factor on isolated myocardial contractile force and action potential duration in guinea pigs]
W J Wu,Q A Xia.Effect of alpha-human atrial natriuretic factor on isolated myocardial contractile force and action potential duration in guinea pigs][J].Acta Physiologica Sinica,1991,43(2):195-198.
Authors:W J Wu  Q A Xia
Institution:Section of Physiology, Zhoushan Health School, Zhejiang.
Abstract:The effect of alpha-hANF on contractile force and action potential duration (APD) of isolated myocardium in guinea pig was investigated. At the level of 20 nmol/L and 40 nmol/L alpha-hANF, the contraction amplitude and rate of contraction phase decreased to a remarkable extent. And at 40 nmol/L, APDs were shortened significantly 20 min after alpha-hANF. The results suggest that there exists a direct inhibitory effect of alpha-hANF on myocardial contractile force and action potential duration.
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