| 一种新的抗人角蛋白单克隆抗体 |
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| 引用本文： | 张荣兴 张容华. 一种新的抗人角蛋白单克隆抗体[J]. 实验生物学报, 1990, 23(4): 487-493 |
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| 作者姓名： | 张荣兴 张容华 |
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| 摘 要： |
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| 关 键 词： | 单克隆抗体 角蛋白 上皮细胞 |
A novel monoclonal antibody against human keratins] |
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| R X Chang,R H Chang,C K Jiang,X M Jin,Q R Zhu,Y Z Pan. A novel monoclonal antibody against human keratins][J]. Acta Biologiae Experimentalis Sinica, 1990, 23(4): 487-493 |
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| Authors: | R X Chang R H Chang C K Jiang X M Jin Q R Zhu Y Z Pan |
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| Affiliation: | Shanghai Institute of Cell Biology, Academia Sinica. |
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| Abstract: | In this paper, we reported a novel monoclonal antibody against human keratins, R 6-2-14. The antigen used for immunization was derived from human callus, keratins in which traditionally are classified as "Soft" keratins. However, when we studied the tissue specificity of this antibody, it was found that it only reacted strongly with "Hard" keratins of various mammalian species, but no detectable cross-reactivity with any of the "Soft" keratins. This antibody may provide a useful tool for the study of hair regeneration, nail regeneration, corn pathology and differentiation of mammalian epidermal derivatives. |
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