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Measurement of 131 I and 125 I by liquid scintillation counting
Authors:E D Bransome  S E Sharpe
Affiliation:Division of Metabolic and Endocrine Disease, Medical College of Georgia, Augusta, Georgia 30902, USA
Abstract:
When aqueous samples are made miscible with a toluene scintillation solution by means of Bio-Solv BBS-3, high 125I and 131I efficiencies can be achieved over a considerable range of “impurity” quenching, and adequate isotope separations can be achieved using liquid scintillation counters with “linear,” “pseudologarithmic,” or “logarithmic” amplification. Using an example of each sort of counter, we have graphically outlined the two somewhat different procedures for choosing the best instrument settings for single- and double-isotope counting. “Linear” instruments, despite a slightly more complex procedure for selection of settings, may offer the advantage, in double-isotope counting, of somewhat greater isotope separations because of the greater attenuation of photo-electron spectra.
Keywords:
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