Gene gain and loss events in Rickettsia and Orientiaspecies |
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Authors: | Kalliopi Georgiades Vicky Merhej Khalid El Karkouri Didier Raoult Pierre Pontarotti |
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Affiliation: | 1.Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, URMITE, CNRS-IRD UMR 6236 IFR48 Faculté de Médecine,Université de la Méditerranée,Marseille,France;2.Evolutionary biology and modeling,LATP UMR CNRS 6632 FR 3098 IFR48 University of Provence,Marseilles,France |
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Abstract: | Background Genome degradation is an ongoing process in all members of the Rickettsiales order, which makes these bacterial species an excellent model for studying reductive evolution through interspecies variation in genome size and gene content. In this study, we evaluated the degree to which gene loss shaped the content of some Rickettsiales genomes. We shed light on the role played by horizontal gene transfers in the genome evolution of Rickettsiales. |
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