Synthesis of a new analog of thymidine for in vivo non-radioactive labeling of DNA. |
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| Authors: | C Rodríguez-Tanty R Pérez J Miranda H Vélez-Castro A Rosado A Macías L Galán D Higginson-Clarke A M Riverón |
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| Affiliation: | Organic Chemistry Department, National Center for Scientific Research, Havana, Cuba. |
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| Abstract: | The introduction of 6-(p-bromobenzoylamino)caproyl radical in the methyl group of 2'-O-deoxythymidine is described. In vivo incorporation of this nucleoside to DNA was determined using a monoclonal antibody that recognized the radical. |
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