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p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress |
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| Authors: | Slavica Tudzarova Paul Mulholland Ayona Dey Kai Stoeber Andrei L. Okorokov |
| Affiliation: | 1. Wolfson Institute for Biomedical Research, Division of Medicine, University College London, London, UK;2. Division of Endocrinology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA;3. Department of Pathology, UCL Cancer Institute, University College London, London, UK |
| Abstract: | |
| Keywords: | CDC7 CDK2 cell cycle DNA damage DNA replication Fbxw7β GSK3β miRNA-192/215 p21 p53 protein degradation |