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Adaptable P body physical states differentially regulate bicoid mRNA storage during early Drosophila development
Institution:1. Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK;2. Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, MO 63110, USA;3. Center for Science and Engineering of Living Systems, Washington University in St. Louis, 1 Brookings Drive, St. Louis, MO 63130, USA;4. Center for Molecular and Cellular Bioengineering, Biotechnology Center, Technische Universität Dresden, Tatzberg 47/49, 01307 Dresden, Germany
Abstract:
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  • Keywords:biomolecular condensates  phase separation  processing bodies  mRNA regulation  axis patterning  intrinsically disordered regions  ribonucleoprotein
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