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Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation
Affiliation:1. Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou 310024, Zhejiang, China;2. Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou 310024, Zhejiang, China;3. Institute of Biology, Westlake Institute for Advanced Study, Hangzhou 310024, Zhejiang, China;4. Department of Experimental Radiation Oncology, the University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA;5. Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China;6. Institute of Basic Medical Science, Westlake Institute for Advanced Study, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China;7. Institute of Systems Biomedicine, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, People’s Republic of China;8. State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing 102206, China;9. Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA 92697, USA
Abstract:
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  • Keywords:Notch pathway  interaction network  LRP1  DLL3  leukemia
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