| Abstract: | In 43 puppies an experimental arterial duct was produced. The animals were observed for 1--2 months and then killed. Their hearts were separately weighed, and their vessels were studied by means of a complex histomicrometry method. In the puppies with the artificially produced arterial duct, hypertrophy of both cardiac ventricles was gradually developing, combined with thickening medial tunica of the coronary arteries at all levels of their branching. Simultaneously, the oblique-longitudinal musculature of the vascular walls grew stronger. In the distributing arteries it occurred at the expense of the muscular fasciculi situated in adventitia, in the resistance arteries--at the expense of the fasciculi situated in intima. The hypertrophic-hyperplastic changes noted in the vessels of the coronary system were connected with cardiac hypertrophy and with disorders of coronary hemodynamics. |
