Flavone glucosides with immunomodulatory activity from the leaves of Pleioblastus amarus |
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Authors: | Wang Hong-Bing Yao Hui Bao Guan-Hu Zhang Hua-Ping Qin Guo-Wei |
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Affiliation: | a Shanghai Institute of Materia Medica, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, People's Republic of Chinab Shanghai Jahwa United Co., Ltd., Shanghai 200056, People's Republic of China |
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Abstract: | Three flavone glucosides, pleiosides A-C, were isolated from the leaves of Pleioblastus amarus, along with two known flavones: tricin and tricetin 3,5-dimethoxy-7-O-β-d-glucopyranoside. Their structures were elucidated by extensive spectral studies. Pleiosides A-C were found to inhibit the proliferation of murine T and significantly stimulate the proliferation of murine B lymphocytes in vitro. |
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Keywords: | Pleioblastus amarus Gramineae Flavone glucosides Immunomodulatory activity |
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