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Flavone glucosides with immunomodulatory activity from the leaves of Pleioblastus amarus
Authors:Wang Hong-Bing  Yao Hui  Bao Guan-Hu  Zhang Hua-Ping  Qin Guo-Wei
Affiliation:
  • a Shanghai Institute of Materia Medica, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China
  • b Shanghai Jahwa United Co., Ltd., Shanghai 200056, People's Republic of China
  • Abstract:
    Three flavone glucosides, pleiosides A-C, were isolated from the leaves of Pleioblastus amarus, along with two known flavones: tricin and tricetin 3,5-dimethoxy-7-O-β-d-glucopyranoside. Their structures were elucidated by extensive spectral studies. Pleiosides A-C were found to inhibit the proliferation of murine T and significantly stimulate the proliferation of murine B lymphocytes in vitro.
    Keywords:Pleioblastus amarus   Gramineae   Flavone glucosides   Immunomodulatory activity
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