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人工诱导海南龙血竭的化学成分研究
引用本文:杨宁,王辉,刘寿柏,王昊,陈惠琴,戴好富,梅文莉.人工诱导海南龙血竭的化学成分研究[J].热带亚热带植物学报,2019,27(2):219-224.
作者姓名:杨宁  王辉  刘寿柏  王昊  陈惠琴  戴好富  梅文莉
作者单位:海南大学热带农林学院, 海口 570228,中国热带农业科学院热带生物技术研究所, 海南省黎药资源天然产物研究与利用重点实验室, 海口 571101,海南大学热带农林学院, 海口 570228,中国热带农业科学院热带生物技术研究所, 海南省黎药资源天然产物研究与利用重点实验室, 海口 571101,中国热带农业科学院热带生物技术研究所, 海南省黎药资源天然产物研究与利用重点实验室, 海口 571101,中国热带农业科学院热带生物技术研究所, 海南省黎药资源天然产物研究与利用重点实验室, 海口 571101,中国热带农业科学院热带生物技术研究所, 海南省黎药资源天然产物研究与利用重点实验室, 海口 571101
基金项目:海南自然科学基金创新研究团队项目(2017CXTD020);国家自然科学基金项目(31400297);中国热带农业科学院基本科研业务费项目(17CXTD-15,1630052016008)资助
摘    要:为了解人工诱导海南龙血树(Dracaena cambodiana)所产血竭的化学成分,从其乙醇提取物中分离得到10个化合物,经波谱分析分别鉴定为socotrin-4?-ol(1)、homoisosocotrin-4?-ol(2)、(E)-3-(3,4-dihydroxybenzylidene)-7-hydroxy-chroman-4-one(3)、5-hydroxy-7-methoxy-3-(4?-hydroxybenzyl)-4-chromanone (4)、3-去氧苏木查耳酮(5)、苏木查耳酮(6)、7,4?-二羟基黄酮(7)、7,4?-二羟基-8-甲基黄酮(8)、丁香树脂醇(9)和邻苯二甲酸二(2-乙基己基)酯(10)。化合物1~10均为首次从人工诱导海南龙血树所产血竭中分离得到,其中化合物8为新天然产物,化合物3~6为首次从血竭中分离得到。化合物7和8对耐甲氧西林金黄色葡萄球菌具有生长抑制作用。

关 键 词:海南龙血树  人工诱导血竭  化学成分  抗菌活性
收稿时间:2018/7/19 0:00:00
修稿时间:2018/9/29 0:00:00

Chemical Constituents from Artificially Induced Dragon's Blood of Dracaena cambodiana
YANG Ning,WANG Hui,LIU Shou-bai,WANG Hao,CHEN Hui-qin,DAI Hao-fu and MEI Wen-li.Chemical Constituents from Artificially Induced Dragon''s Blood of Dracaena cambodiana[J].Journal of Tropical and Subtropical Botany,2019,27(2):219-224.
Authors:YANG Ning  WANG Hui  LIU Shou-bai  WANG Hao  CHEN Hui-qin  DAI Hao-fu and MEI Wen-li
Institution:Institute of Tropical Agriculture and Forestry, Hainan University, Haikou 570228, China,Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China,Institute of Tropical Agriculture and Forestry, Hainan University, Haikou 570228, China,Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China,Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China,Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China and Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China
Abstract:In order to understand the chemical constituents of artificially induced dragon''s blood of Dracaena cambodiana, ten compounds were isolated from the ethanol extract. On the basis of spectral data, their structures were indentified as socotrin-4''-ol (1), homoisosocotrin-4''-ol (2), (E)-3-(3,4-dihydroxybenzylidene)-7-hydroxy- chroman-4-one (3), 5-hydroxy-7-methoxy-3-(4''-hydroxybenzyl)-4-chromanone (4), 3-deoxysappa­nchalcone (5), sappanchalcone (6), 7,4''-dihydroxyflavone (7), 7,4''-dihydroxy-8-methylflavone (8), syringares­inol (9) and bis (2-ethylhexyl) phthalate (10). All compounds were isolated from artificially induced dragon''s blood of Dracaena cambodiana for the first time, compound 8 was a new natural product, compounds 3-6 were isolated from dragon''s blood for the first time. The compounds 7 and 8 had inhibitory activities against methicillin-resistant Staphylococcus aureus (MRSA).
Keywords:Dracaena cambodiana  Artificially induced dragon''s blood  Chemical constituent  Antibacterial activity
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