Software for genome mapping by fingerprinting techniques

A genome mapping package has been developed for reading andassembling data from clones analysed by restriction enzyme fragmentationand polyacrylamide gel electrophoresis. The package comprises:data entry; matching; assembly; statistical analysis; modelling.Data entry can be either manual or by a semiautomatic systembased on a scanning densitometer. The primary emphasis in theanalytical routines is on flexibility and interactive convenience,so that the operator has full knowledge of and control overthe growing map, but a variety of automatic options are included.The package continually grows to meet the needs of the Caenorhabditisproject. Received on July 17, 1987; accepted on November 20, 1987