Les examens cardiaques en tomographie par émission de positons |
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| Authors: | P-Y Marie W Djaballah N Didot G Karcher |
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| Institution: | 1. Service de médecine nucléaire, hôpital de Brabois, CHU de Nancy, allée du Morvan, 54511 Vand?uvre cedex, France;2. Faculté de médecine, université de Nancy, 54000 Nancy, France;3. Inserm U961, 54000 Nancy, France;4. Inserm U947, 54000 Nancy, France;1. UFR santé, université de Picardie Jules Verne, 80000 Amiens, France;2. Unité TEP, service de médecine nucléaire, CHU d’Amiens, CHU Sud, avenue Laennec, 80054 Amiens cedex 1, France;1. Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, Connecticut;2. Atlantic Medical Imaging, Galloway, New Jersey;1. Biomedical Image Technologies Lab., DIE, ETSI Telecomunicación, Universidad Politécnica de Madrid, Madrid, Spain;2. Centro Investigación Biomédica en Red: Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain;3. Faculty of Electrical Engineering, Czech Technical University in Prague, Czech Republic;4. Seccion Hepatobiliopancreatica, Servicio de Cirugía General I, Hospital General Universitario Gregorio Marañón, Madrid, Spain;5. Servicio de Radiodiagnóstico, Hospital General Universitario Gregorio Marañón, Madrid, Spain;6. Departamento de Bioingeniería e Ingeniería Aeroespacial, Universidad Carlos III de Madrid, Madrid, Spain;7. Instituto de Investigación Sanitaria Gregorio Marañón, CIBERSAM, Madrid, Spain;1. IAME Inserm U1137, association pour l’étude et la prévention de l’endocardite infectieuse, Inserm CIC 1425, AP–HP, hôpital universitaire Bichat, 75018 Paris, France;2. Service de médecine nucléaire, GH Bichat-Claude Bernard, Assistance publique–hôpitaux de Paris (AP–HP), DHU FIRE, 46, rue Henri-Huchard, 75018 Paris, France;3. Université Paris Diderot, UFR de médecine site Bichat, 16, rue Henri-Huchard, 75018 Paris, France;1. Pelé Pequeno Príncipe Research Institute, Av. Silva Jardim, 1632, Curitiba PR 80250-060, Brazil;2. National Science Center ‘Kharkov Institute of Physics and Technology’, Akademicheskaya 1, Kharkiv 61108, Ukraine;3. Federal University of Technology, Av. Sete de Setembro, 3165, Curitiba PR 80230-90, Brazil |
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| Abstract: | Cardiac positron emission tomography (PET) is yet considered as a reference imaging technique but remains poorly used in clinical practice. At the present time, the advantages of cardiac PET investigations are far to be evident, when compared with conventional tomoscintigraphy (SPECT), except for perfusion imaging in the obese and for viability assessment in case of very severe cardiac dysfunction. However, this situation might quickly move because of an enhanced availability of PET imaging, dramatic technical progresses and promising new tracers. In particular, the last-generation PET-cameras allow reaching spatial resolutions and detection sensitivities, which are now spectacularly higher than those from conventional SPECT imaging. In addition, the list mode recording allows the subsequent images reconstruction to be synchronized to cardiac cycle but also to respiratory cycle; and the quantifications of myocardial perfusion flow and of coronary flow reserve are now available in clinical routine. Furthermore, new tracers labelled with fluorine-18 are under development, especially for perfusion investigations, and kinetics properties of these new tracers are dramatically enhanced when compared with current perfusion SPECT tracers. |
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