Biosynthesis and activity of DNA polymerase throughout the mitotic cycle of Physarum polycephalum |
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| Authors: | A M MacNicol G R Banks R A Cox |
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| Affiliation: | Laboratory of Developmental Biochemistry, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, England |
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| Abstract: | ![]()
Measurements of DNA polymerase protein levels and polymerase activity through the naturally synchronous mitotic cycle of Physarum polycephalum show that active DNA polymerase-alpha is synthesized throughout the G2 phase, in step with the profile of general protein biosynthesis. Three main components of P. poly-cephalum DNA polymerase of 200, 112 and 70 kDa were found to be immunologically related. |
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