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Bile acids in asymmetric synthesis and chiral discrimination
Authors:Olga Bortolini  Giancarlo Fantin  Marco Fogagnolo
Affiliation:1. Dipartimento di Chimica, Università della Calabria, Rende (CS), Italy;2. Dipartimento di Chimica, Università di Ferrara, Ferrara, Italy
Abstract:An overview on the use of bile acid‐based compounds able to catalyze transformations, control the stereochemical course of a given reaction, recognize and bind other molecules, is presented. The recent developments in inclusion discrimination of chiral and achiral guests and enantioselective recognition achieved by bile acid are described with suitable examples. Chirality 2010. © 2009 Wiley‐Liss, Inc.
Keywords:bile acids  asymmetric synthesis  enclathration  host‐guest complexation  racemate resolution
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