COVID-19 mRNA vaccines |
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| Authors: | Qingrui Huang Jiawei Zeng Jinghua Yan |
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| Institution: | 1. CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China;2. University of Chinese Academy of Sciences, Beijing 101408, China |
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| Abstract: | The ongoing COVID-19 pandemic and its unprecedented global societal and economic disruptive impact highlight the urgent need for safe and effective vaccines. Taking substantial advantages of versatility and rapid development, two m RNA vaccines against COVID-19 have completed late-stage clinical assessment at an unprecedented speed and reported positive results. In this review, we outline keynotes in m RNA vaccine development, discuss recently published data on COVID-19 m RNA vaccine candidates, focusing on those in clinical trials and analyze future potential challenges. |
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