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Experimental Analysis of E2BB (LTIIb) Signal Peptide in Secretory Production of Reteplase in Escherichia coli
Authors:Mousavi  Pegah  Morowvat  Mohammad Hossein  Mostafavi-Pour  Zohreh  Aram  Farzaneh  Malekzadeh  Kianoosh  Nezafat  Navid  Ghasemi  Younes
Institution:1.Department of Medical Biotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran
;2.Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, P.O. Box 71345-1583, Shiraz, Iran
;3.Recombinant Protein Laboratory, Department of Biochemistry, Medical School, Shiraz University of Medical Sciences, Shiraz, Iran
;4.Department of Medical Genetics, School of Medical Sciences, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
;5.Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran
;6.Institute of Biotechnology, Shiraz University, Shiraz, Iran
;7.Molecular Medicine Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
;8.Fertility and Infertility Research Center, Hormozgan University of Medical Sciences, P.O. Box 7919693116, Bandar Abbas, Iran
;
Abstract:International Journal of Peptide Research and Therapeutics - Recombinant reteplase is the truncated form of tissue plasminogen activator. Signal peptides play a pivotal role in the secretion of...
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