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Isopoly(S-carboxymethyl-L-cysteine) derivatives of nucleic acid bases: effects of D-cysteine derivatives on the interaction with DNA.
Authors:Y Inaki  H Nitomi  N Tohnai
Affiliation:Material and Life Science, Graduate School of Osaka University, Suita, Japan.
Abstract:Isopoly(S-carboxymethyl-D-cysteine) derivatives of nucleic acid bases were prepared to study the effect of chirality on the complex formation with oligo-DNA. The D-cysteine unit in the L-cysteine oligomer caused decrease of Tm for the complex with DNA.
Keywords:
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