Isopoly(S-carboxymethyl-L-cysteine) derivatives of nucleic acid bases: effects of D-cysteine derivatives on the interaction with DNA. |
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| Authors: | Y Inaki H Nitomi N Tohnai |
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| Affiliation: | Material and Life Science, Graduate School of Osaka University, Suita, Japan. |
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| Abstract: | Isopoly(S-carboxymethyl-D-cysteine) derivatives of nucleic acid bases were prepared to study the effect of chirality on the complex formation with oligo-DNA. The D-cysteine unit in the L-cysteine oligomer caused decrease of Tm for the complex with DNA. |
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