Poecillastrin D: a new cytotoxin of the chondropsin class from marine sponge Jaspis serpentina |
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| Authors: | Takemoto Daisaku Takekawa Yoshihiko Soest Rob W M van Fusetani Nobuhiro Matsunaga Shigeki |
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| Affiliation: | Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, USA. |
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| Abstract: | ![]()
Poecillastrin D (2) was isolated together with poecillastrin C (1) from the deep sea sponge, Japsis serpentina. Its structure was elucidated to be that of a macrolide lactam by spectroscopic methods. These compounds showed potent cytotoxicity against various tumor cell lines. |
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