MicroRNA regulation of stem cell fate |
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| Authors: | Li Qintong Gregory Richard I |
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| Affiliation: | Stem Cell Program, Children's Hospital Boston, Boston, MA 02115, USA. |
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| Abstract: | MicroRNAs modulate target gene expression and are essential for normal development, but how does this pathway impact cell fate decisions? In this issue of Cell Stem Cell, Ivey et al. (2008) find that muscle-specific microRNAs repress nonmuscle genes to direct embryonic stem cell differentiation to mesoderm and muscle. |
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