Statistical significance of some complex nucleotide combinations: a comparison of DNA models |
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| Authors: | Suboch, G.M. Sprizhitsky, Yu.A. |
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| Affiliation: | Institute of Molecular Genetics, USSR Academy of Sciences Kurchatov Square, Moscow 123182, USSR |
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| Abstract: | DNA is modelled as a sequence of nucleotide runs. This modelis shown to provide a more adequate description of the observedfrequencies of occurrence of local homopurine-homopyrimidinemirror repeats than the second-order homogeneous Markov chainmodel. The procedure is described for estimating the statisticalsignificance of the occurrence of some complex nucleotide combinationsin DNA. Received on August 21, 1989; accepted on August 25, 1989 |
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