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Front Cover: Dual‐wavelength hybrid optoacoustic‐ultrasound biomicroscopy for functional imaging of large‐scale cerebral vascular networks (J. Biophotonics 9/2018)
Authors:Johannes Rebling  Héctor Estrada  Sven Gottschalk  Gali Sela  Michael Zwack  Georg Wissmeyer  Vasilis Ntziachristos  Daniel Razansky
Institution:1. Institute of Biological and Medical Imaging (IBMI), Helmholtz Center Munich, Neuherberg, Germany;2. Faculty of Medicine and Faculty of Electrical Engineering, Technical University of Munich, München, Germany
Abstract:We present a hybrid dual‐wavelength optoacoustic and ultrasound bio‐microscope capable of rapid transcranial visualization of morphology and oxygenation status of large‐scale cerebral vascular networks. Imaging of entire cortical vasculature in mice is achieved with single capillary resolution and complemented by simultaneously acquired pulse‐echo ultrasound microscopy scans of the mouse skull. The new approach holds potential to facilitate studies into neurological and vascular abnormalities of the brain. Further details can be found in the article by Johannes Rebling, Héctor Estrada, Sven Gottschalk, et al. ( e201800057 ).

Keywords:blood vessels  brain  cerebral  microscopy  photoacoustics  ultrasound
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