Chromosomal localization of the human interleukin 1 alpha (IL-1 alpha) gene |
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Authors: | W S Modi A Masuda M Yamada J J Oppenheim K Matsushima S J O'Brien |
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Institution: | Biological Carcinogenesis Development Program, Frederick Cancer Research Facility, Maryland 21701-1013. |
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Abstract: | The human interleukin 1 alpha gene was assigned to chromosome 2 using Southern transfer analysis of human-rodent somatic cell hybrid DNAs. The gene was regionally localized to 2q12-21 using in situ hybridization to metaphase chromosomes. These results indicate that the IL-1 alpha gene maps to the same general region on the long arm of chromosome 2 as the IL-1 beta gene, which has been previously assigned. |
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