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Computational Modelling of Dapsone Interaction With Dihydropteroate Synthase in Mycobacterium leprae; Insights Into Molecular Basis of Dapsone Resistance in Leprosy |
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| Authors: | Sundeep Chaitanya V Madhusmita Das Pritesh Bhat Mannam Ebenezer |
| Affiliation: | 1. Research Officer, Department of Laboratories, Molecular Biology and Immunology Division, The Schieffelin Institute of Health‐Research and Leprosy Center (SIH‐R&LC), Karigiri, Vellore, Tamil Nadu, India;2. Applications Scientist, Schrodinger, Inc., Near KMWA Vidya Niketan, Mahalakshmipuram, Bangalore, India;3. The Schieffelin Institute of Health‐Research and Leprosy Center (SIH‐R&LC), Karigiri, Vellore, Tamil Nadu, India |
| Abstract: | |
| Keywords: | DIHYDROPTEROATE SYNTHASE DAPSONE DRUG RESISTANCE MULTIDRUG THERAPY POINT MUTATIONS MOLECULAR DOCKING BINDING AFFINITIES |