The efflux rate of norepinephrine from platelets and its relation to blood pressure |
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| Authors: | I Mattiasson B Mattiasson B Hood |
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| Affiliation: | 1. Dept. of Medicine, University of Lund, Malmö General Hospital, Malmö, Sweden;2. Biochemistry 2, Chemical Center, University of Lund, Lund, Sweden |
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| Abstract: | The uptake and efflux rate of norepinephrine in platelets have been studied in 63 individuals, 48 men and 15 women. 40 of these had a diastolic blood pressure ?95 mm Hg. If the initial efflux rate, k, was correlated to the diastolic blood pressure a highly significant relationship (r = 0.748 p<0.001) was obtained, i.e. a high diastolic blood pressure is correlated to a rapid efflux of norepinephrine from platelets. No correlation was found between uptake values and diastolic blood pressure. |
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