| 心肌梗塞后大鼠左心室舒张性能和顺应性的动态改变 |
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| 引用本文： | 王俊宏,杨继声,卢兴. 心肌梗塞后大鼠左心室舒张性能和顺应性的动态改变[J]. 中国应用生理学杂志, 1987, 0(4) |
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| 作者姓名： | 王俊宏 杨继声 卢兴 |
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| 作者单位： | 西安医科大学病理生理教研室(王俊宏，杨继声)，西安医科大学病理生理教研室(卢兴) |
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| 摘 要： | 心室的舒张性能和顺应性是心脏功能的两个重要方面。为了查明心肌梗塞后这两个特性的演变规律,我们在离体条件下观察了大鼠心脏舒张性能和顺应性在左冠状动脉结扎后2秒到21天之间的动态过程。实验表明,结扎冠状动脉后,左室舒张性能指标有明显改变(T值延长,-dp/dtmax降低),在恢复期未见明显改善;左室顺应性的变化有明显的时相性,表现为先有一过性增高,之后明显降低,继而回升到接近对照水平,到恢复期则明显增高。
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| 关 键 词： | 心肌梗塞 心室舒张性能 左心室顺应性 |
THE DYNAMIC CHANGES OF LEFT VENTRICULAR DIASTOLIC FUNCTION AND CHAMBER COMPLIANCE AFTER MYPOCARDIAL INFARCTION IN RATS |
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| Wang Junhong,et al.. THE DYNAMIC CHANGES OF LEFT VENTRICULAR DIASTOLIC FUNCTION AND CHAMBER COMPLIANCE AFTER MYPOCARDIAL INFARCTION IN RATS[J]. Chinese journal of applied physiology, 1987, 0(4) |
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| Authors: | Wang Junhong et al. |
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| Abstract: | To reveal their dynamic changes after myocardial infarction, the left ventricular diastolic function and chamber compliancs were observed with isolated working heart perfusion apparatus ranging from 2 seconds to 21 days after left coronary artery ligation in male rats. The results indicated: 1) Time constant of left ventricular pressure falling during isovolumic period was elongated and -dp/dt max decreased significantly after the coronary ligation, there was no significant recovery in the observed period. 2 ) Left ventricular chamber complianca had a time-depsndence change after coronary artery ligation, it showed a strikingly decrease prec eded by a slightly increase, and increased again in the recovery stage. |
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| Keywords: | myocardial infarction diastolic functions left ventricular compliance |
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