| 人乳头瘤病毒的致瘤性及机制 |
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| 引用本文： | 钱永红,黄夏,蒋创. 人乳头瘤病毒的致瘤性及机制[J]. 微生物与感染, 2011, 6(4): 252-255 |
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| 作者姓名： | 钱永红 黄夏 蒋创 |
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| 作者单位： | 1. 南京医科大学附属苏州医院苏州市立医院母子保健中心,苏州,215000
2. 常熟市第二人民医院,常熟,215500 |
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| 摘 要： | 高危型人乳头瘤病毒(HPV)可能引发多种癌症,公认的如宫颈癌和宫颈上皮内瘤变.近年来的研究表明,HPV还与头颈部鳞癌、食管癌及乳房癌等的发生密切相关.HPV引起头颈部鳞癌的机制在某种程度上与宫颈癌相似,但又有所不同.因此,阐明HPV的致癌机制对于HPV相关肿瘤的治疗具有重要意义.
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| 关 键 词： | 人乳头瘤病毒 宫颈癌 头颈部鳞癌 食管癌 乳房癌 |
Human papillomavirus in human carcinogenesis |
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| QIAN Yong-Hong,HUANG Xia,JIANG Chuang. Human papillomavirus in human carcinogenesis[J]. Journal of Microbes and Infection, 2011, 6(4): 252-255 |
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| Authors: | QIAN Yong-Hong HUANG Xia JIANG Chuang |
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| Affiliation: | QIAN Yong-Hong1,HUANG Xia2,JIANG Chuang1 1. Department of Gynecology and Obsterics,Suzhou Municipal Hospital Suzhou Medical Center for Maternity and Child Health,Nanjing Medical University,Suzhou 215000,China,2. Changshu NO.2 People's Hospital,Changshu 215500 |
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| Abstract: | High-risk types of human papillomavirus (HPV) may cause various tumors. The causative link between high-risk HPV and cervical cancer has been well elucidated. Recent studies have shown that HPV DNA is detectable in head and neck squamous cell carcinoma (HNSCC), esophageal carcinoma, as well as breast cancer. The mechanisms underlying HPV infection in HNSCC may be similar but not identical to that in cervical cancer. Understanding the mechanisms underlying HPV-associated carcinogenesis will be important for ... |
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| Keywords: | Human papillomavirus Cervical cancer Head and neck squamous cell carcinoma Esophageal carcinoma Breast cancer |
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