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Comparison between human and armadillo Paracoccidioides brasiliensis isolates by random amplified polymorphic DNA analysis |
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| Authors: | Sano Ayako Tanaka Reiko Yokoyama Koji Franco Marcello Bagagli Eduardo Montenegro Mario Rubens Mikami Yuzuru Miyaji Makoto Nishimura Kazuko |
| Institution: | 1.Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1-8-1, Inohana, Chiba, Chuo-ku, Chiba, 260-8673, Japan ;2.Department of Pathology, Faculty of Medicine, Paulista Medical School, UNIFESP, Rua Botucatu, 740 Vila Clementino, 04034-900, S?o Paulo, Capital, Brazil ;3.epartment of Microbiology, Institute of Biology, S?o Paulo State University, UNESP, 18603-970, Botucatu,S?o Paulo, Brazil ;4.Department of Pathology, Faculty of Medicine, S?o Paulo State University, UNESP, 18603-970, Botucatu, S?o Paulo, Brazil ; |
| Abstract: | Sixty-three Paracoccidioides brasiliensis isolates obtained from three nine-banded armadillos ( Dasypus novemcinctus), one Amazonian armadillo's and 19 clinical isolates were compared by random amplified polymorphic DNA analysis with the primer OPG-19. The isolates were divided into three major clusters, I, II and III. Coincidences between human and armadillo isolates were observed in clusters I and II. Cluster III consisted only of armadillos' isolates. The results suggested that (I) humans may acquire P. brasiliensis infection by contact with armadillo's environment, (II) there may be P. brasiliensis genotypes peculiar to the animal, and (III) individual armadillos may be infected with P. brasiliensis cells with different genotypes. This revised version was published online in June 2006 with corrections to the Cover Date. |
| Keywords: | armadillo Paracoccidioides brasiliensis PCR RAPD |
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