| 激光照射胚泡对家兔和小鼠的抗早孕研究 |
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| 引用本文： | 丁爱华,陈惠玲,连少辉,崔可心,郑怀美.激光照射胚泡对家兔和小鼠的抗早孕研究[J].生理学报,1987(5). |
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| 作者姓名： | 丁爱华 陈惠玲 连少辉 崔可心 郑怀美 |
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| 作者单位： | 上海医科大学妇产科医院病理教研室
(丁爱华，崔可心)，中国科学院上海生理研究所
(陈惠玲)，中国科学院上海生物化学研究所
(连少辉)，上海医科大学妇产科医院病理教研室(郑怀美) |
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| 摘 要： | 本文在家兔、小鼠上探索了激光的抗旱孕效应,观察到血卟啉衍生物(HPD)和激光的光化效应能使早期胚泡完全坏死和吸收,无流血和晚期流产现象,通过PNQ_3荧光分光光度计测定HPD在胚胎组织中的荧光谱,证实HPD对胚胎组织有亲和力,其对滋养叶细胞比对宫壁组织的亲和力大4倍,借以解释激光光化效应抗早孕的可能机理。
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| 关 键 词： | 激光 血卟啉 抗旱孕 荧光谱 |
STUDIES ON TERMINATING EARLY PREGNANCY OF LASER IN RABBITS AND MICE |
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| DING AI-HUA,CHEN HUI-LING,LIAN SHAO-HUI,CUI KE-XING,ZANG HUAI-MEI.STUDIES ON TERMINATING EARLY PREGNANCY OF LASER IN RABBITS AND MICE[J].Acta Physiologica Sinica,1987(5). |
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| Authors: | DING AI-HUA CHEN HUI-LING LIAN SHAO-HUI CUI KE-XING ZANG HUAI-MEI |
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| Institution: | DING AI-HUA,CHEN HUI-LING,LIAN SHAO-HUI,CUI KE-XING,ZANG HUAI-MEI Department of Pathology,Shanghai Medical University Hospital of Gynecology and Obstetrics Shanghai Institute of Physiology,Academia Sinica Shanghai Institute of Biochemistry,Academia Sinica |
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| Abstract: | Effect of laser on terminating early pregnancy in rabbits and mice showedthat laser in combination with HPD could induce necrosis of blastocysts and completeabsorption. The anti-fertility efficiency of the combined treatment was moreeffective than that of the He-Ne laser or the HPD treatment alone. The fluroescencespectrum of HPD determined by PNQ_3 showed that its affinity to embryonic tissuewas about 4 times greater than that to uterine tissue. These may underlie themechanism of anti-early pregnancy of the laser. |
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| Keywords: | laser hematoporphyrin terminating early pregnancy fluorescence spectrum |
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