Fragile sites,chromosome evolution,and human neoplasia |
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| Authors: | Rosa Miró Inmaculada Concepción Clemente Carmen Fuster José Egozcue |
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| Institution: | (1) Departament de Biologia Cel.lular i Fisiologia, Universitat Autònoma de Barcelona, Bellaterra (Barcelona), Spain;(2) Institut de Biologia Fonamental  Vincent Villar Palasí , Universitat Autònoma de Barcelona, Ballaterra (Barcelona), Spain |
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| Abstract: | Summary In a study of the possible relationship between human fragile sites, chromosomal rearrangements related to neoplasia, and chromosome regions involved in evolutionary changes, we have found that 17 fragile sites related to cancer, 15 fragile sites not related to cancer, and 17 non-fragile regions also related to human malignancy correspond or are close to bands involved in rearrangements that have taken place during chromosomal evolution in primates. |
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