| 创伤后应激障碍（PTSD）的生物学研究概述 |
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| 引用本文： | 张娅玲,白艳秋,彭正午,颜志鹏,谭庆荣.创伤后应激障碍（PTSD）的生物学研究概述[J].生物磁学,2011(1):172-175,168. |
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| 作者姓名： | 张娅玲 白艳秋 彭正午 颜志鹏 谭庆荣 |
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| 作者单位： | [1]第四军医大学西京医院心身科,陕西西安710032 [2]中国科学院北京基因组研究所,北京100029 |
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| 基金项目： | 全军＂十一五＂指令性课题（08BMZX04-3）（08Z031）; 国家自然科学基金（30870886） |
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| 摘 要： | 创伤后应激障碍（posttraumatic stress disorder,PTSD）是灾害后精神及行为障碍的一种重要表现形式,具有发病率及患病率高、病程长、疗效差等特点,严重影响了临床救治。对于创伤后应激障碍发病机制及其防治的研究日益受到关注。致力于PTSD研究的研究者,从行为学、神经内分泌等宏观研究,到形态学、细胞分子生物学等功能研究,再到临床实验研究,做了大量的工作,得到了许多具有实际指导意义的结果。本文针对国内外研究者近年来在这方面的研究现状进行综述,从宏观上为PTSD后续的研究提供一些循证的证据。
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| 关 键 词： | 创伤后应激障碍（posttraumatic stress disorder PTSD） PTSD动物模型 内分泌学 影像学 形态学 |
Biology Research of posttraumatic stress disorder |
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| ZHANG Ya-ling,BAI Yan-qiu,PENG Zheng-wu,YAN Zhi-peng,TAN Qing-Rong.Biology Research of posttraumatic stress disorder[J].Biomagnetism,2011(1):172-175,168. |
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| Authors: | ZHANG Ya-ling BAI Yan-qiu PENG Zheng-wu YAN Zhi-peng TAN Qing-Rong |
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| Institution: | 1 Department of Psychosomatics,Xi＇jing Hospital,Fourth Military Medical University,Xi＇an,Shaanxi Province 710032,PR China; 2 Beijing Institute of Genomics,Chinese Academy of Sciences,Beijing 100029,PR China) |
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| Abstract: | Posttraumatic stress disorder（PTSD） is an important represatation of psychiatric and behavior disorder after stress,and it characterized by high incidence,high rate of sicken,long course of diseases,and can not well curative effect.There were more attention to the mechanism,prevention and cure of PTSD.Researchers devoted themselves to PTSD study have got many practise directive signification results from there study,including macroscopic research such as behivior,endocrinology;structural and functional research based on morphology and cell-molecular biology;clinical trial.Here,we briefly review the recent basic research of PTSD,in order to give a glance to the research in PTSD. |
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| Keywords: | Posttraumatic stress disorder（PTSD） animal models of PTSD endocrinology imaging morphology |
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