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Prenatal selection and fetal development disturbances occurring in carriers of G6PD deficiency
Authors:D Toncheva  M Tzoneva
Institution:(1) Department of Medical Genetics, Medico-Biological Institute, Bulgarian Academy of Medicine, Sofia, Bulgaria
Abstract:Summary The incidence of spontaneous abortions in women with glucose-6-phosphate dehydrogenase (G6PD) deficiency was studied. In 78 families where the wife was a heterozygous carrier of G6PD deficiency the percentage of unsuccessful pregnancies with spontaneous abortions occurring in the first trimester was higher (21.7%, calculated from 258 pregnancies) than in the control group (9.3%), calculated from 678 pregnancies.
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