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Multiple roles of Equarin during lens development
Authors:Xiaohong Song  Hideaki Tanaka  Kunimasa Ohta
Affiliation:Division of Developmental Neurobiology, Faculty of Life Sciences, Kumamoto University, , Chuo‐ku, Kumamoto, 860‐8556 Japan
Abstract:Since the days of Hans Spemann, the ocular lens has served as one of the most important developmental systems for elucidating the fundamental processes of induction and differentiation. Lens is an important source of signals that influence the eye development and a variety of genes expressed by the lens have been identified. The identification of additional molecule(s), especially secreted ones that might mediate signals, will extend our knowledge of the molecular mechanisms of eye and lens development. Here, we will introduce a soluble molecule, Equarin, and discuss its vital role in multiple aspects of lens development.
Keywords:development  Equarin  fibroblast growth factors  lens
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