| 病毒离子通道——一种新的抗病毒靶 |
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| 引用本文： | 袁玉华,王学谦,耿运琪,陈启民.病毒离子通道——一种新的抗病毒靶[J].生物化学与生物物理进展,2004,31(10):861-864. |
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| 作者姓名： | 袁玉华 王学谦 耿运琪 陈启民 |
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| 作者单位： | 南开大学生命科学学院,天津,300071 |
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| 摘 要： | 病毒离子通道蛋白是一种在病毒生命周期中起多种作用的小跨膜蛋白，可在宿主细胞膜上形成选择性离子通道，一些离子通道阻滞剂能阻滞这些离子通道，从而抑制这些病毒的繁殖，因而病毒离子通道蛋白可作为新的抗病毒作用靶.
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| 关 键 词： | 病毒，离子通道，抗病毒靶 |
| 收稿时间： | 2004/4/16 0:00:00 |
| 修稿时间： | 2004/6/30 0:00:00 |
Virus Ion Channels:a Kind of New Target for Antivirus Drug Action |
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| YUAN Yu-Hu,WANG Xue-Qian,GENG Yun-Qi and CHEN Qi-Min.Virus Ion Channels:a Kind of New Target for Antivirus Drug Action[J].Progress In Biochemistry and Biophysics,2004,31(10):861-864. |
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| Authors: | YUAN Yu-Hu WANG Xue-Qian GENG Yun-Qi and CHEN Qi-Min |
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| Institution: | College of Life Science, Nankai University, Tianjin 300071, China;College of Life Science, Nankai University, Tianjin 300071, China;College of Life Science, Nankai University, Tianjin 300071, China;College of Life Science, Nankai University, Tianjin 300071, China |
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| Abstract: | Viral ion channels are short transmembrane proteins, which have multifunctional roles in the life cycle of virus.It has been shown to form selective ion channel in host cell membrane.Some ion channel blockers are able to block the channels and inhibit the ion channels activity which may lead to diminished virus production. It suggests that the virus ion channels could be a kind of highly relevant target for antiviral drug action. |
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| Keywords: | virus ion channel target for antiviral drug action |
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