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Bone Marrow Involvement in a Patient with Paracoccidioidomycosis: A Rare Presentation of Juvenile Form
Authors:Graziella Hanna Pereira  Aline Queiroz Santos  Miriam Park  Patricia Rady Muller  Soraia Padua  Raquel Ferrari Marchesi  Vera Lucia Aldred
Affiliation:1. Department of Infectious Diseases and Infection Control, Brigadeiro Hospital, S?o Paulo, SP, Brazil
2. Depatment of Pediatric Hematology, Brigadeiro Hospital, S?o Paulo, SP, Brazil
3. Department of Pathology, University of S?o Paulo, S?o Paulo, SP, Brazil
Abstract:Paracoccidioides brasiliensis rarely shows bone marrow involvement and its response to treatment with itraconazole in children needs further assessment. We describe here a child with a juvenile disseminated form of paracoccidioidomycosis, which showed reticuloendothelial system involvement and the presence of Paracoccidioides brasiliensis in the bone marrow. The patient showed an effective and rapid response to itraconazole therapy.
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