Autoinducer-2 Production in Campylobacter jejuni Contributes to Chicken Colonization |
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| Authors: | Beatriz Qui ones, William G. Miller, Anna H. Bates, Robert E. Mandrell |
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| Affiliation: | Beatriz Quiñones, William G. Miller, Anna H. Bates, and Robert E. Mandrell |
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| Abstract: | ![]()
Inactivation of luxS, encoding an AI-2 biosynthesis enzyme, in Campylobacter jejuni strain 81-176 significantly reduced colonization of the chick lower gastrointestinal tract, chemotaxis toward organic acids, and in vitro adherence to LMH chicken hepatoma cells. Thus, AI-2 production in C. jejuni contributes to host colonization and interactions with epithelial cells. |
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