Levels of zinc and lipid peroxidation in acute coronary syndrome |
| |
| Authors: | Gurkan Cikim Halit Canatan M Ferit Gursu Funda Gulcu Giyaseddin Baydas A Erhan Kilicoglu |
| |
| Institution: | (1) Department of Biochemistry, Mustafa Kemal University, Hatay, Turkey;(2) Department of Cardiology College of Medicine, Mustafa Kemal University, Hatay, Turkey;(3) Department of Medical Biology, Firat University, Elaziğ, Turkey;(4) Department of Biochemistry, Firat University, Elaziğ, Turkey;(5) Department of Physiology, College of Medicine, Firat University, Elaziğ, Turkey |
| |
| Abstract: | The present study was carried out on 20 female patients diagnosed with acute coronary syndrome (ACS). The control group was
composed of 20 healthy female volunteers. Plasma malondialdehyde (MDA) levels and serum zinc (Zn), total cholesterol, low-density
lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and VLDL-cholesterol, Lp(a), Apo-A1, and Apo-B were determined in all patients and controls. Plasma MDA levels were determined to be significantly high in patients
with ACS compared to the controls (1.75±0.27 vs 0.8±0.43 nmol/mL; p<0.05). On the other hand, Zn levels in patients with ACS were determined to be significantly low compared to the control
group (67.9±14.8 vs 101.8±22.4 mg/dL; p<0.05). There was a statistically significant negative correlation between MDA and Zn levels in patients with ACS (r=−0.678, p<0.05). Other lipid parameters were significantly altered in patients with ACS compared to the controls (p<0.05). In conclusion, Zn and lipid peroxidation levels are important in patients with ACS and they must be monitored during
diagnosis and treatment of these patients. |
| |
| Keywords: | Acute coronary syndrome lipid peroxidation MDA zinc |
| 本文献已被 PubMed SpringerLink 等数据库收录！ |
|
