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Further evidence for the proposed way of spermatogonial stem cell renewal in the rat and the mouse
Authors:D. G. de Rooij
Affiliation:(1) Department of Histology, State University Medical School, Utrecht, The Netherlands
Abstract:Summary By means of 3H-thymidine and autoradiography it could be established that in rats and mice the A1, A2 and A3 spermatogonia do not give rise to a significant number of stem cells.The number of A0 spermatogonia was found to be circa 20% of the number of A0+A1 spermatogonia in the rat and circa 10% in the mouse.The author wishes to thank Prof. Dr. M. T. Jansen and Dr. M. F. Kramer for helpful discussions and Mr. J. G. van Essen for technical assistance.
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