Biotransformation of monoterpenes and sesquiterpenes by cell suspension cultures of Achillea millefolium L. ssp. millefolium |
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Authors: | Figueiredo A. Cristina Almendra M. João Barroso José G. Scheffer Johannes J. C. |
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Affiliation: | (1) Departamento de Biologia Vegetal, Faculdade de Ciências de Lisboa, Bloco C2, 1780 Campo Grande, Lisbon, Portugal;(2) Division of Pharmacognosy, Leiden/Amsterdam Center for Drug Research, Leiden University, Gorlaeus Laboratories, PO Box 9502, 2300 Leiden, RA, The Netherlands |
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Abstract: | The transformation capacity of Achillea millefolium L. ssp. millefolium (yarrow) cell suspension cultures was investigated using geraniol (50mg/l) and borneol, menthol, thymol and farnesols (25mg/l) as substrates. Apart from converting these substrates into several biotransformation products, the cell suspension cultures were also able to glycosylate both the substrates and the biotransformation products. aa]Key Words bb]Achillea millefolium L. ssp. millefolium bb]Yarrow bb]Compositae bb]Biotransformation bb]Glycosylation bb]Geraniol bb]Borneol bb]Menthol bb]Thymol bb]Farnesols |
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