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Severe acute coronary spasm following intracoronary radiation for in-stent restenosis: A case report
Affiliation:1. Cardiovascular Division, Brigham and Women''s Hospital, Harvard Medical School, Boston, MA, United States;2. Mechanical and Industrial Engineering, Northeastern University, Boston, MA, United States;1. Cranfield University, Silsoe College, Silsoe, Bedford MK45 4DT, UK;2. Department of Food Science and Technology, University College Cork Cork, Ireland;1. Department of Radiology and Nuclear Medicine, Marienhospitals Herne, University Hospital of Ruhr, Universität Bochum, Bochum, Germany;2. Department of Radio-Oncology, Marienhospitals Herne, University Hospital of Ruhr, Universität Bochum, Bochum, Germany
Abstract:Intracoronary radiation therapy is currently the only available treatment for the prevention of recurrence of in-stent restenosis. We report a case of severe coronary spasm after excimer laser angioplasty, balloon angioplasty, and intracoronary gamma radiation in the right coronary artery (RCA) that resulted in an acute myocardial infarction. Treatment with 600 μg of intracoronary nitroglycerin resulted in minimal improvement; therefore, diltiazem 400 μg was administered intracoronary with total resolution of the spasm, restoring normal coronary blood flow without trace of acute dissection or thrombus inside the artery.
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