Polyamine prevention of inhibition of rat liver isoleucyl-tRNA formation by poly(G), poly(I) or ribosomes. |
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Authors: | K Igarashi M Tanaka K Eguchi S Hirose |
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Institution: | Faculty of Pharmaceutical Sciences, Chiba University, Yayoi-cho, Chiba, Japan |
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Abstract: | It is shown that rat liver isoleucyl-tRNA formation in the presence of Mg2+ is inhibited by poly(G), poly(I) or ribosomes and that this inhibition is prevented by polyamines. The inhibition is found to be noncompetitive with respect to tRNA. |
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