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Unfaithful DNA polymerase caught in the act |
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| Authors: | Jiricny Josef |
| Affiliation: | Institute of Molecular Cancer Research, University of Zürich, August Forel-Strasse 7, CH-8008 Zurich, Switzerland. |
| Abstract: | The 3D structures of all 12 mispairs formed in the active site of a DNA polymerase help explain their differential effects on polymerase stalling and on translocation of the primer terminus to the enzyme's proofreading site. |
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