Elevated choline concentration in neonatal plasma |
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| Authors: | Steven H Zeisel Michael F Epstein Richard J Wurtman |
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| Institution: | 1. Laboratory of Neuroendocrine Regulation Department of Nutrition and Food Science Massachusetts Institute of Technology Cambridge, Massachusetts 02139, USA;2. Joint Program in Neonatology Boston Hospital for Women Boston, Massachusetts 02115, USA |
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| Abstract: | Plasma choline concentrations were measured in humans, rats, and rabbits within the first few hours of life, before any food was ingested. Neonatal animals and humans had markedly elevated plasma choline levels compared to adult animals or humans. Possible mechanisms responsible for this elevation are discussed and possible consequences for brain function, lung function, and growth are presented. |
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