逆转录病毒载体在基因工程疫苗方面的应用

逆转录病毒载体是根据逆转录病毒的特性设计出的一种病毒表达载体，以其能够整合到宿主细胞染色体上并能稳定表达目的基因而被视为基因运载最有效的工具。目前广泛应用于基因治疗、外源基因表达、基因工程疫苗等方面。主要综述了逆转录病毒载体在基因工程疫苗方面的应用现状及前景，为该载体在生物医学领域方面的应用提供有价值的参考。

The Use of Retroviral Vector in Genetically Engineering Vaccine

Retroviral vector was a virus expression vector which was designed by some characteristics of retrovirus. Because it can integrate into the chromosome of host cells and stably express the interesting gene. It was considered as the most efficient means of delivering a interest gene into human cells. Presently, retroviral vector was extensively used for gene therapy, exogenous gene expression and genetically engineering vaccine. The use of retroviral expression vector in genetically engineering vaccine and its applied perspect were mainly discussed,which provide valuable reference for the application of biomedicine.